Remember to fill the frame with your artwork. Leave a little bit of breathing room around the outside edges so that you can see everything, but don't have too many distractions in the background. If you have a vertically-oriented piece of art, set your camera vertically on the tripod. The camera's image sensor will be filled up vertically, and you won't have to crop your shot with computer software. If you have a horizontally-oriented piece of artwork, such as a painting, then tilt your camera horizontally and fill up the frame of the image sensor in a horizontal format. Try to crop as best as you can in-camera.